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style="font-size:16px;">锛?锛夎偪鐦ゅ井鐜涓庤偪鐦ゅ共缁嗚優涔嬮棿鐩镐簰璋冩帶鐨勫垎瀛愭満鍒跺強鑲跨槫杞Щ鍜屽鍙戣繃绋嬬爺绌讹紱</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">锛?锛夎偪鐦ょ壒寮傛€ф姂鍒跺皬鍒嗗瓙鑽墿鐨勭爺鍙戝強闈跺悜鑽墿杞戒綋鐨勭爺绌讹紱</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">锛?锛夋柊鍨嬭偪鐦よ泲鐧界柅鑻楀拰DNA鐤嫍鍙婃姉鑲跨槫铻嶅悎铔嬬櫧鐨勭爺绌躲€侟/span></p><p style="text-align:left;"><span style="color:#953734;font-weight:bold;font-size:18px;">浜屻€佹暀鑲茶儗鏅?/span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">1989.07-1992.07  涓婃捣浜ら€氬ぇ瀛﹀尰瀛﹂櫌锛堝師涓婃捣绗簩鍖荤澶у锛夌粏鑳炵敓鐗╁涓庡疄楠屾牳鍖诲绯伙紝鑾峰尰瀛︾瀛﹀崥澹浣岦/span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">1986.07-1989.07  閲嶅簡鍖荤澶у涓村簥鐢熺墿鍖栧涓撲笟锛岃幏鍖诲纭曞+瀛︿綅</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">1978.02-1982.02  閲嶅簡鍖荤澶у锛岃幏鍖诲瀛﹀+瀛︿綅</span></p><p style="text-align:left;"><span style="color:#953734;font-weight:bold;font-size:18px;">涓夈€佸伐浣滅粡鍘咟/span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">2007.3-2019.7          鍗楀紑澶у鍖诲闄紝闄㈤暱锛屽崥澹敓瀵煎笀</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">2007.3-2008.12            缇庡浗Scripps鐮旂┒鎵€鍏嶇柅绯伙紝鍓暀鎺 (Associate Professor)</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">2001.5-2007.3          缇庡浗Scripps鐮旂┒鎵€鍏嶇柅绯伙紝鍔╃悊鏁欐巿 (Assistant Professor)</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">1999.5-2001.5          缇庡浗Scripps鐮旂┒鎵€鍏嶇柅绯伙紝璧勬繁鍗氬+鍚 (Senior Postdoc)</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">1996.5-1999.5          缇庡浗Scripps鐮旂┒鎵€鍏嶇柅绯伙紝鍗氬+鍚 (Postdoc)</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">1992.7-1996.5          澶嶆棪澶у涓婃捣鍖诲闄紙鍘熶笂娴峰尰绉戝ぇ瀛︼級锛 鍔╂暀锛屽壇鏁欐巿</span></p><p style="text-align:left;"><span style="color:#953734;font-weight:bold;font-size:18px;">鍥涖€佷富鎸佷富瑕佺鐮旈」鐩?/span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">瀵瑰彂灞曚腑鍥藉绉戞妧鎻村姪椤圭洰鈥滀腑娉扮敓鐗╃柅鑻楄浆鍖栧尰瀛︿腑蹇冣€濓紝璧锋骞存湀锛?015.12-2018.11锛岄」鐩礋璐d汉锛汓/span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">鍥藉閲嶅ぇ绉戝鐮旂┒璁″垝锛?73璁″垝锛夆€滆偪鐦ゅ共缁嗚優鍦ㄥ疄浣撹偪鐦ゅ彂灞曚腑鐨勮皟鎺ф満鍒剁爺绌垛€濓紝璧锋骞存湀锛 2013.01-2017.12锛岄甯瀛﹀锛汓/span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">鍥藉鍥介檯绉戞妧鍚堜綔涓撻」鈥滄柊鍨嬩钩鑵虹檶鏃╂湡棰勮绯荤粺鐨勫缓绔嬪強闃叉不鏂规硶鐨勫悎浣滅爺绌垛€濓紝 璧锋骞存湀锛?012.06-2015.05锛岄」鐩礋璐d汉銆侟/span></p><p style="text-align:left;"><span style="color:#953734;font-weight:bold;font-size:18px;">浜斻€侀儴鍒嗗彂琛ㄨ鏂囷紙2011-2016锛堻/span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">1.Zhang Z., Yin J., Yang J., Shen W., Zhang C., Mou W., Luo J., Yan H., Sun P., Luo Y., Tian Y., Xiang R. miR-885-5p suppresses hepatocellular carcinoma metastasis and inhibits Wnt/尾-catenin signaling pathway. Oncotarget. 2016 Oct 12. doi: 10.18632/oncotarget.12602.</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">2.Zhao, Shuangtao; Dong, Xiaoli; Shen, Wenzhi; Ye, Zhen; Xiang, Rong; Machine learning-based classification of diffuse large B-cell lymphoma patients by eight gene expression profiles. Cancer Medicine, 2016 May, 5(5): 837-52.</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">3.Ye Zhen, Guo Chunlei, Shen Wenzhi, Zhao Shuangtao, Luo Na, Wang Rongrong, Luo Xiaohe, Niu Haiying, Luo Dehong, Jiang Shan, Tan Xiaoyue, Xiang Rong . Clinicopathologic significance of legumain overexpression in cancer: a systematic review and meta-analysis. Scientific Reports, 2015 Nov 26, 5(16599).</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">4.Chang A, Chen Y, Shen W, Gao R, Zhou W, Yang S, Liu Y, Luo Y, Chuang TH, Sun P, Liu C, Xiang R. Ifit1 Protects Against Lipopolysaccharide and D-galactosamine-Induced Fatal Hepatitis by Inhibiting Activation of the JNK Pathway. Journal of Infectious Diseases. 2015 Nov 1, 212(9):1509-1520.</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">5.Xu, Y., Zhang, S., Niu, H., Ye, Y., Hu, F., Chen, S., Li, X., Luo, X., Jiang, S., Liu, Y., Chen, Y., Li, J., Xiang, R. & Li, N. STIM1 accelerates cell senescence in a remodeled microenvironment but enhances the epithelial-to-mesenchymal transition in prostate cancer. Scientific Reports, 2015 Aug 10, 5(11754).</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">6.Ze Liu, Min Xiong, Junbo Gong, Yan Zhang, Nan Bai, Yunping Luo, Luyuan Li, Yuquan Wei,Yanhua Liu, Xiaoyue Tan & Rong Xiang. Legumain protease-activated TAT-liposome cargo for targeting tumors and their microenvironment. Nature Communications, 2014 Jun 27, 5:4280.</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">7.Chen S, Li X, Lu D, Xu Y, Mou W, Wang L, Chen Y, Liu Y, Li X, Li LY, Liu     L, Stupack D, Reisfeld RA, Xiang R & Li N. SOX2 regulates apoptosis through MAP4K4-Survivin signaling pathway in human lung cancer cells. Carcinogenesis. 2014 Mar; 35(3):613-23.</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">8.Li X, Xu Y, Chen Y, Chen S, Jia X, Sun T, Liu Y, Li X, Xiang R, Li N. SOX2 promotes tumor metastasis by stimulating epithelial-to-mesenchymal transition via regulation of WNT/尾-catenin signal network. Cancer Letters. 2013 Aug 19; 336(2):379-89.</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">9.Bai N, Zhang C, Liang N, Zhang Z, Chang A, Yin J, Li Z, Luo N, Tan X, Luo N, Luo Y, Xiang R, Li X, Reisfeld RA, Stupack D, Lv D, Liu C. Yes-associated protein (YAP) increases chemosensitivity of hepatocellular carcinoma cells by modulation of p53. Cancer Biology & Therapy. 2013 Jun; 14(6):511-20.</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">10.Liu Z, Lv D, Liu S, Gong J, Wang D, Xiong M, Chen X, Xiang R, Tan X. Alginic acid-coated chitosan nanoparticles loaded with legumain DNA vaccine: effect against breast cancer in mice. PLoS One. 2013;8(4) :e60190.</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">11.Zhang C, Bai N, Chang A, Zhang Z, Yin J, Shen W, Tian Y, Xiang R, Liu C. ATF4 is directly recruited by TLR4 signaling and positively regulates TLR4-trigged cytokine production in human monocytes. Cellular & Molecular Immunology. 2013 Jan; 10(1):84-94.</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">12.Su W, Wang L, Zhou M, Liu Z, Hu S, Tong L, Liu Y, Fan Y, Kong D, Zheng Y, Han Z, Wu JC, Xiang R, Li Z. Human embryonic stem cell-derived endothelial cells as cellular delivery vehicles for treatment of metastatic breast cancer. Cell Transplantation. 2013; 22(11): 2079-90.</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">13.Manqian Zhou, Lina Wang, Weijun Su, Lingling Tong, Yanhua Liu, Fan Yan, Yizhou Zheng, Hui Zhao, Rong Xiang, Zongjin Li. Assessment of therapeutic efficacy of liposome mediated gene delivery by molecular imaging for cancer therapy. Journal of Biomedical Nanotechnology. 2012 Oct; 8 (5): 742-50.</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">14.Si Chen; Yingxi Xu; Yanan Chen; Xuefei Li; Wenjun Mou; Lina Wang; Yanhua Liu;  Ralph A. Reisfeld; Rong  Xiang; Dan Lv; Na Li. SOX2 gene regulates the transcriptional network of oncogenes and inhibits tumorigenesis of human lung cancer cells. PLoS One. 2012;7(5):e36326.</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">15.Lina Wang, Si Chen, Mingna Zhang, Na Li, Yanan Chen, Weijun Su, Yanhua Liu, Dan  Lu, Sanglin Li, Yixuan Yang, Zongjin Li, Pengpeng Qu, Huaidong Hu, Rong  Xiang. Legumain: a Biomarker for the Diagnosis and Prognosis of Human Ovarian Cancer.  Journal of Cellular Biochemistry. 2012 Aug;113(8):2679-86.</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">16.Lu D, Chen S, Tan X, Li N, Liu C, Li Z, Liu Z, Stupack DG, Reisfeld RA, Xiang R, Fra-1 promotes breast cancer chemosensitivity by driving cancer stem cells from dormancy. Cancer Research. 2012 Jul 15; 72(14):3451-6.</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">17.Lina Wang, Weijun Su, Ze Liu, Manqian Zhou, Si Chen, Yanan Chen, Dan Lu, Yanhua Liu, Fan Yan, Joesph C. Wu, Rong Xiang, Zongjin Li. CD44 Antibody Targeted Liposome for Molecular Imaging and Therapy of Hepatocellular Carcinoma. Biomaterials. 2012 Jul; 33(20):5107-14.</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">18.Jiajia Hu, Kunhua Qin, Yan Zhang, Junbo Gong, Na Li, Dan Lv, Rong Xiang and Xiaoyue Tan. Downregulation of transcription factor Oct4 induces an epithelial-to-mesenchymal transition via enhancement of Ca(2+) influx in breast cancer cells. Biochemical &  Biophysical Research Communications. 2011 Aug 12; 411(4):786-91.</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">19.Xianpei Jia, Xuefei Li, Yingxi Xu, Shu Zhang, Wenjun Mou, Yanhua Liu, Yin Liu, Dan Lv, Cheng-Hu Liu, Xiaoyue Tan, Rong Xiang and Na Li. SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cell. Journal of Molecular Cell Biology. 2011 Aug;3(4):230-8.</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">20.Xiang R, Liao D, Cheng T, Zhou H, Shi Q, Chuang TS, Markowitz D, Reisfeld RA, Luo Y. Downregulation of transcription factor SOX2 in cancer stem cells suppresses growth and metastasis of lung cancer. British Journal of Cancer. 2011 Apr 26;104(9):1410-7.</span></p><p style="text-indent:2em;text-align:left;"><span style="font-size:16px;">21.Su W, Zhou M, Zheng Y, Fan Y, Wang L, Han Z, Kong D, Zhao RC, Wu JC, Xiang R, Li Z. Bioluminescence reporter gene imaging characterize human embryonic stem cell-derived teratoma formation. Journal of Cellular Biochemistry 2011 Mar; 112(3):840鈥?48.</span></p></div> </div> </div> </div> </div> </div> </div> <div class="footer"> <div class="footer-con"> <div class="w"> <div class="logo"> <img src="/_upload/tpl/03/7d/893/template893/images/logo1.png" /> </div> <div class="addr"> <h2>鑱旂郴鎴戜滑</h2> <p> 澶╂触甯傚崡寮€鍖哄崼娲ヨ矾94鍙 鍗楀紑澶у鍖诲闄↑br/> 閭紪锛?00071<br/> 缁煎悎鍔炲叕瀹わ細022-23502554 <br/> 鏈鏁欏鍔炲叕瀹わ細022-23503994<br/> 鐮旂┒鐢熷姙鍏锛?22-83662909<br/> 瀛︾敓鍔炲叕瀹わ細022-23508098 </p> </div> <div class="addr addr1"> <h2></h2> <p> 澶╂触娴锋渤鏁欒偛鍥尯鍚岀牃璺?8鍙饵br/> 閭紪锛?00350<br/> 鐢佃瘽锛?22-85358549 </p> </div> <div class="wx"> <a href="javascript:;" class="wx1"><img src="/_upload/tpl/03/7d/893/template893/images/wx.png" /></a> <a href="javascript:;" target="_blank"><img src="/_upload/tpl/03/7d/893/template893/images/wb.png" /></a> </div> <div class="clear"></div> <div class="copyright"> Copyright 漏Nankai University All Rights Reserved. </div> </div> </div> </div> </div> <div class="gotop"> <img src="/_upload/tpl/03/7d/893/template893/images/gotop.jpg"> </div> <div id="wx" style="display:none;"><img src="/_upload/tpl/03/7d/893/template893/images/gfwx.jpg" /></div> <script type="text/javascript" src="/_upload/tpl/03/7d/893/template893/js/layer/layer.js"></script> <script type="text/javascript" src="/_upload/tpl/03/7d/893/template893/js/common.js"></script> <script type="text/javascript"> $(function () { }); </script> </body> </html> <img src="/_visitcount?siteId=113&type=3&articleId=69035" style="display:none" width="0" height="0"></image>